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Magic™ Membrane Protein Human TMC6 (Transmembrane channel like 6) Full Length (CAT#: MPC0949K) Made to Order

Datasheet
This product is a 90 kDa Human TMC6 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • TMC6
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 90 kDa
  • TMD
  • 10
  • Sequence
  • MAQPLAFILDVPETPGDQGQGPSPYDESEVHDSFQQLIQEQSQCTAQEGL
    ELQQREREVTGSSQQTLWRPEGTQSTATLRILASMPSRTIGRSRGAIISQ
    YYNRTVQLRCRSSRPLLGNFVRSAWPSLRLYDLELDPTALEEEEKQSLLV
    KELQSLAVAQRDHMLRGMPLSLAEKRSLREKSRTPRGKWRGQPGSGGVCS
    CCGRLRYACVLALHSLGLALLSALQALMPWRYALKRIGGQFGSSVLSYFL
    FLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPVCTGLELLTGAGCF
    THTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPYNMPLAYLSTVGVS
    FFITCITLVYSMAHSFGESYRVGSTSGIHAITVFCSWDYKVTQKRASRLQ
    QDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALGCAV
    AVHVFSEFMIQSPEAAGQEAVLLVLPLVVGLLNLGAPYLCRVLAALEPHD
    SPVLEVYVAICRNLILKLAILGTLCYHWLGRRVGVLQGQCWEDFVGQELY
    RFLVMDFVLMLLDTLFGELVWRIISEKKLKRRRKPEFDIARNVLELIYGQ
    TLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAPRRPWLASHMST
    VFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRH
    LEAAGPRVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVI
    CLLKEQISNEGEDKIFLINKLHSIYERKEREERSRVGTTEEAAAPPALLT
    DEQDA

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • TMC6
  • Full Name
  • Transmembrane channel like 6
  • Introduction
  • Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.
  • Alternative Names
  • EV1; lnc; EVER1; EVIN1; LAK-4P; TNRC6C-AS1; transmembrane channel-like protein 6; TNRC6C antisense RNA 1; epidermodysplasia verruciformis 1; epidermodysplasia verruciformis protein 1; expressed in activated T/LAK lymphocytes; protein LAK-4; TMC6; Transmembrane channel like 6

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