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Magic™ Membrane Protein Human UGT1A10 (UDP glucuronosyltransferase family 1 member A10) Full Length (CAT#: MPC4430K) Made to Order

Datasheet
This product is a made-to-order Human UGT1A10 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • UGT1A10
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 1
  • Sequence
  • MARAGWTSPVPLCVCLLLTCGFAEAGKLLVVPMDGSHWFTMQSVVEKLIL
    RGHEVVVVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKA
    QAQSIFSLLMSSSSGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPF
    DTCGLIVAKYFSLPSVVFTRGIFCHHLEEGAQCPAPLSYVPNDLLGFSDA
    MTFKERVWNHIVHLEDHLFCQYLFRNALEIASEILQTPVTAYDLYSHTSI
    WLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIV
    VFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVK
    WLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKR
    METKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVE
    PLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVA
    FITFKCCAYGYRKCLGKKGRVKKAHKSKTH

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • UGT1A10
  • Full Name
  • UDP glucuronosyltransferase family 1 member A10
  • Introduction
  • This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has glucuronidase activity on mycophenolic acid, coumarins, and quinolines.
  • Alternative Names
  • UGT1A10; GNT1; UGT1; UDPGT; UGT1A; UGT1J; UGT-1A; UGT-1J; UGT1.1; UGT1A1; UGT1-01; UGT1-10; UGT1.10; hUG-BR1; UDP-glucuronosyltransferase 1A10; Bilirubin-specific UDPGT isozyme 1; UDP glucuronosyltransferase 1 family, polypeptide A10; UDP glycosyltransferase 1 family, polypeptide A10; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1-10; UDP-glucuronosyltransferase 1-A; UDP-glucuronosyltransferase 1-J; UDP-glucuronosyltransferase 1A1; UDP glucuronosyltransferase family 1 member A10

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