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Magic™ Membrane Protein Human UGT2A1 (UDP glucuronosyltransferase family 2 member A1 complex locus) Full Length (CAT#: MPC4452K) Made to Order

Datasheet
This product is a made-to-order Human UGT2A1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • UGT2A1
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • TMD
  • 1
  • Sequence
  • MLNNLLLFSLQISLIGTTLGGNVLIWPMEGSHWLNVKIIIDELIKKEHNV
    TVLVASGALFITPTSNPSLTFEIYRVPFGKERIEGVIKDFVLTWLENRPS
    PSTIWRFYQEMAKVIKDFHMVSQEICDGVLKNQQLMAKLKKSKFEVLVSD
    PVFPCGDIVALKLGIPFMYSLRFSPASTVEKHCGKVPYPPSYVPAVLSEL
    TDQMSFTDRIRNFISYHLQDYMFETLWKSWDSYYSKALGRPTTLCETMGK
    AEIWLIRTYWDFEFPRPYLPNFEFVGGLHCKPAKPLPKEMEEFIQSSGKN
    GVVVFSLGSMVKNLTEEKANLIASALAQIPQKVLWRYKGKKPATLGNNTQ
    LFDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDN
    IAHMKAKGAAVEVNLNTMTSVDLLSALRTVINEPSYKENAMRLSRIHHDQ
    PVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVIGFLLVCVT
    TAIFLVIQCCLFSCQKFGKIGKKKKRE

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • UGT2A1
  • Full Name
  • UDP glucuronosyltransferase family 2 member A1 complex locus
  • Introduction
  • The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This gene shares exon structure with the UDP glucuronosyltransferase 2A2 family member, which encodes N-terminally distinct isoforms.
  • Alternative Names
  • UGT2A1; UDPGT2A1; UDP-glucuronosyltransferase 2A1; UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus; UDP glycosyltransferase 2 family, polypeptide A1; uridine diphosphate glycosyltransferase 2 family, member A1; UDP glucuronosyltransferase family 2 member A1 complex locus

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