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Magic™ Recombinant Mouse Mcu Membrane Protein in Virus-Like Particles (MP-VLPs) (CAT#: S01YF-0622-KX100)

This product is recombinant Mouse Mcu in VLPs form. This product is produced from HEK293 by co-expressing the retroviral structural core polyprotein (gag) and the target membrane protein. MP-VLPs display highly-expressed copies of membrane proteins in their native conformation, providing an alternative to membrane protein stable cell lines, membrane preparations, detergent-solubilized proteins and other membrane protein preparation strategies. MP-VLPs can be used for a wide range of applications in antibody production, antibody discovery, antibody characterization, binding assays and functional assays.

Product Specifications

  • Host Species
  • Mouse
  • Target Protein
  • Mcu
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • TMD
  • 2
  • Sequence
  • AHQRPASWQSVGAAYCSTVVPSDDVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDRGIDRVAIYSPDGVRVAASTGIDLLLLDDFKLVINDLTYHVRPPKRDLLSHEDAATLNDVKTLVQQLYTTLCIEQHQLNKERELVERLEDLKQQLAPLEKVRIEISRKAEKRTTLVLWGGLAYMATQFGILARLTWWEYSWDIMEPVTYFITYGSAMAMYAYFVMTRQEYVYPEARDRQYLLFFHKGAKKSRFDLEKYNQLKDAIAQAEMDLKRLRDPLQVHLPLRQIGEKE

Product Description

  • Application
  • ELISA; Antibody Production; Antibody Discovery; Antibody Characterization; Binding Assays; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • 10xHis tag at the C-terminus
  • Protein Format
  • Membrane Protein-Virus Like Particles (MP-VLPs)
  • Buffer
  • PBS, 6% Trehalose, pH 7.4

Target

  • Target Protein
  • Mcu
  • Full Name
  • Mitochondrial calcium uniporter
  • Introduction
  • Predicted to enable calcium channel activity; identical protein binding activity; and uniporter activity. Involved in mitochondrial calcium ion transmembrane transport and positive regulation of mitochondrial calcium ion concentration. Located in mitochondrion. Part of calcium channel complex. Is expressed in several structures, including central nervous system; genitourinary system; gut; limb segment; and vertebral axis musculature. Orthologous to human MCU (mitochondrial calcium uniporter).
  • Alternative Names
  • Gm64; AV064928; C10orf42; Ccdc109a; 2010012O16Rik; D130073L02Rik; calcium uniporter protein, mitochondrial; coiled-coil domain containing 109A

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