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NativeExtract™ Human ADGRG4 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX310)

Datasheet
This product is recombinant Human ADGRG4 protein in native nanodisc form. The synthetic compound we developed can solubilize the ADGRG4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ADGRG4
  • Protein Length
  • Full length
  • Molecular Weight
  • 333.4kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • ADGRG4
  • Full Name
  • Adhesion G protein-coupled receptor G4
  • Introduction
  • This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy.
  • Alternative Names
  • ADGRG4; PGR17; GPR112; RP1-299I16; adhesion G-protein coupled receptor G4; G protein-coupled receptor 112; probable G-protein coupled receptor 112; Adhesion G protein-coupled receptor G4

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