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NativeExtract™ Human CCKBR Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX257)

Datasheet
This product is recombinant Human CCKBR protein in native nanodisc form. The synthetic compound we developed can solubilize the CCKBR protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CCKBR
  • Protein Length
  • Full length
  • Molecular Weight
  • 48.4kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CCKBR
  • Full Name
  • Cholecystokinin B receptor
  • Introduction
  • This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. Alternative splicing results in multiple transcript variants. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors.
  • Alternative Names
  • GASR; CCK-B; CCK2R; gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK2 receptor; cholecystokinin-2 receptor; gastrin receptor; CCKBR; Cholecystokinin B receptor

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