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NativeExtract™ Human CD151 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX418)

Datasheet
This product is recombinant Human CD151 protein in native nanodisc form. The synthetic compound we developed can solubilize the CD151 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD151
  • Protein Length
  • Full length
  • Molecular Weight
  • 28.3 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CD151
  • Full Name
  • CD151 molecule (Raph blood group)
  • Introduction
  • The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
  • Alternative Names
  • CD151; GP27; MER2; RAPH; SFA1; PETA-3; TSPAN24; CD151 antigen; CD151 antigen (Raph blood group); hemidesmosomal tetraspanin CD151; membrane glycoprotein SFA-1; platelet surface glycoprotein gp27; platelet-endothelial cell tetraspan antigen 3; platelet-endothelial tetraspan antigen 3; tetraspanin-24; tspan-24; CD151 molecule (Raph blood group)

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