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NativeExtract™ Human CLDN5 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX414)

Datasheet
This product is recombinant Human CLDN5 protein in native nanodisc form. The synthetic compound we developed can solubilize the CLDN5 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLDN5
  • Protein Length
  • Full length
  • Molecular Weight
  • 23.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CLDN5
  • Full Name
  • Claudin 5
  • Introduction
  • This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
  • Alternative Names
  • CLDN5; AWAL; BEC1; TMVCF; TMDVCF; CPETRL1; claudin-5; transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome; Claudin 5

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