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NativeExtract™ Human CLDN7 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX413)

Datasheet
This product is recombinant Human CLDN7 protein in native nanodisc form. The synthetic compound we developed can solubilize the CLDN7 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLDN7
  • Protein Length
  • Full length
  • Molecular Weight
  • 22.9 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • CLDN7
  • Full Name
  • Claudin 7
  • Introduction
  • This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.
  • Alternative Names
  • CLDN7; CLDN-7; CEPTRL2; CPETRL2; Hs.84359; claudin-1; claudin-7; clostridium perfringens enterotoxin receptor-like 2; epididymis secretory sperm binding protein; Claudin 7

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