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NativeExtract™ Human F2RL3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX381)

Datasheet
This product is recombinant Human F2RL3 protein in native nanodisc form. The synthetic compound we developed can solubilize the F2RL3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • F2RL3
  • Protein Length
  • Full length
  • Molecular Weight
  • 41.1 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • F2RL3
  • Full Name
  • F2R like thrombin or trypsin receptor 3
  • Introduction
  • This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients.
  • Alternative Names
  • F2RL3; PAR4; proteinase-activated receptor 4; F2R like thrombin/trypsin receptor 3; PAR-4; coagulation factor II (thrombin) receptor-like 3; protease-activated receptor-4; thrombin receptor-like 3; F2R like thrombin or trypsin receptor 3

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