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NativeExtract™ Human FZD3 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX269)

Datasheet
This product is recombinant Human FZD3 protein in native nanodisc form. The synthetic compound we developed can solubilize the FZD3 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • FZD3
  • Protein Length
  • Full length
  • Molecular Weight
  • 76.3kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • FZD3
  • Full Name
  • Frizzled class receptor 3
  • Introduction
  • This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of this protein is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. This gene is a susceptibility locus for schizophrenia.
  • Alternative Names
  • Fz-3; frizzled-3; frizzled 3, seven transmembrane spanning receptor; frizzled family receptor 3; frizzled homolog 3; FZD3; Frizzled class receptor 3

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