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NativeExtract™ Human GPR132 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX379)

Datasheet
This product is recombinant Human GPR132 protein in native nanodisc form. The synthetic compound we developed can solubilize the GPR132 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • GPR132
  • Protein Length
  • Full length
  • Molecular Weight
  • 42.5 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • GPR132
  • Full Name
  • G protein-coupled receptor 132
  • Introduction
  • This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • G2A; probable G-protein coupled receptor 132; G2 accumulation protein; GPR132; G protein-coupled receptor 132

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