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NativeExtract™ Human LPAR1 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX179)

This product is recombinant Human LPAR1 protein in native nanodisc form. The synthetic compound we developed can solubilize the LPAR1 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • LPAR1
  • Protein Length
  • Full length
  • Molecular Weight
  • 41.1kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • LPAR1
  • Full Name
  • Lysophosphatidic acid receptor 1
  • Introduction
  • The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Many transcript variants encoding a few different isoforms have been identified for this gene.
  • Alternative Names
  • EDG2; LPA1; VZG1; edg-2; vzg-1; Gpcr26; Mrec1.3; rec.1.3; LPA receptor 1; LPA-1; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2; lysophosphatidic acid receptor Edg-2; ventricular zone gene 1; LPAR1; Lysophosphatidic acid receptor 1

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