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NativeExtract™ Human SLC2A4 Membrane Protein (Full length, Super Nanodisc) (CAT#: S01YF-1023-KX423)

Datasheet
This product is recombinant Human SLC2A4 protein in native nanodisc form. The synthetic compound we developed can solubilize the SLC2A4 protein from membrane while retaining the native structure.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SLC2A4
  • Protein Length
  • Full length
  • Molecular Weight
  • 54.6 kDa

Product Description

  • Activity
  • Yes
  • Application
  • ELISA; SPR Binding Assays; Phage Display Screening; Immunity; Functional Assays
  • Expression Systems
  • HEK293 expression system
  • Tag
  • Flag tag at the C-terminus
  • Protein Format
  • Native Nanodisc
  • Buffer
  • 20 mM Tris-HCl, 150 mM NaCl, pH 8.0

Target

  • Target Protein
  • SLC2A4
  • Full Name
  • Solute carrier family 2 member 4
  • Introduction
  • This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
  • Alternative Names
  • GLUT4; solute carrier family 2, facilitated glucose transporter member 4; glucose transporter type 4, insulin-responsive; insulin-responsive glucose transporter type 4; solute carrier family 2 (facilitated glucose transporter), member 4; GLUT-4; SLC2A4; Solute carrier family 2 member 4

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