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- Anti-TACSTD2 (clone C16)-VC-PABC-Aur0101 ADC
Anti-TACSTD2 (clone C16)-VC-PABC-Aur0101 ADC (CAT#: ADC-W-563)
This ADC product is comprised of an anti-TACSTD2 monoclonal antibody (clone C16) conjugated via a VC-PABC linker to Aur0101.
- Product Information
- ADC Target
- ADC Antibody
- ADC Linker
- ADC payload drug
- Antibody clone #
- C16
- Name
- TACSTD2
- Alternative Names
- TACSTD2; tumor-associated calcium signal transducer 2; EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1; epithelial glycoprotein-1; cell surface glycoprotein TROP2; cell surface glycoprotein Trop-2; pancreatic carcinoma marker protein GA7331; pancreatic ca
- Target Entrez Gene ID
- 4070
- Target UniProt ID
- P09758
- Overview
- This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.
- Overview
- Anti-TACSTD2 Antibody, clone # C16
- Clone #
- C16
- Species Reactivity
- Human
- Name
- VC-PABC (valine-citrulline-p-aminobenzylcarbamate)
- Description
- Peptide linkers, belonging to Enzymatically cleavable linkers, combine greater systemic stability with rapid enzymatic release of the drug in the target cell. The scission of peptidic bonds relies on lysosomal proteolytic enzymes, which have very low activities in blood due to endogenous inhibitors and the unfavorably high pH value of blood.
- Name
- Aur0101
For Research Use Only. NOT FOR CLINICAL USE.
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Other Products
Same Target
CAT# | Product Name | Linker | Payload |
ADC-W-292 | Anti-TACSTD2 (clone 7E6)-PEG6-MMAD ADC | PEG6 ((Propylene Glycol)-6-propionyl) | MMAD (monomethyl auristatin D) |
ADC-W-539 | Anti-TACSTD2 (clone C16)-PEG6-Aur3377 ADC | Amino-PEG6-based linker | Aur3377 |
ADC-W-538 | Anti-TACSTD2 (clone C16)-PEG6-MMAD ADC | Amino-PEG6-based linker | MMAD (monomethyl auristatin D) |
ADC-W-290 | Anti-TACSTD2 (clone 7E6)-AcLys-VC-PABC-MMAD ADC | AcLys-VC- PABC (Acetyl-lysine-valine-citrulline-p-aminobenzyloxycarbonyl) | MMAD (monomethyl auristatin D) |
ADC-W-293 | Anti-TACSTD2 (clone 7E6)-AcLys-VC-PABC-0101 | AcLys-VC- PABC (Acetyl-lysine-valine-citrulline-p-aminobenzyloxycarbonyl) | 2-methylalanyl-N-[(3R,4S,5S)-3-methoxy-1-{(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-{[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]amino}propyl]pyrrolidin-1-yl}-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide) |
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