Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Fab-scFv-Fc) (FABVC-002)

Recombinant Anti-Ad fiber knob x Anti-CD40 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-Ad fiber knob antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-CD40 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Datasheet INQUIRY

Specifications

Targets

Ad Fiber Knob & CD40

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Acute myeloid leukaemic (AML)

Targets

Target 1

Ad Fiber Knob

Alternative Names

Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber

Target 2

CD40

Gene ID

958

UniProt ID

P25942

Alternative Names

CD40; CD40 molecule; p50; Bp50; CDW40; TNFRSF5

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Related products of "Ad Fiber Knob & CD40"

See other bsAb targets related to "Ad Fiber Knob"

See other bsAb targets related to "CD40"

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Fab-scFv-Fc) (FABVC-002). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-002)

Specifications

Targets

Customer Reviews and Q&As