Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Single-chain Diabody) (SCDB-002)

Recombinant Anti-Ad fiber knob x Anti-CD40 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.

Datasheet INQUIRY

Specifications

Targets

Ad Fiber Knob & CD40

Type

Single-chain Diabody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Acute myeloid leukaemic (AML)

Targets

Target 1

Ad Fiber Knob

Alternative Names

Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber

Target 2

CD40

Gene ID

958

UniProt ID

P25942

Alternative Names

CD40; CD40 molecule; p50; Bp50; CDW40; TNFRSF5

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (Single-chain Diabody) (CAT#: SCDB-002)

Specifications

Targets

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