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3D Hanging Spheroid Plate-based Cytotoxicity Assay Service

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Creative Biolabs has introduced a toxicity assay based on three-dimensional hanging spheroid plates by facilitating spheroid formation as well as isolating unbound and dead cells during the assay.

3D Hanging Spheroid Plate: A Specialized Cell Culture Tool

The 3D hanging spheroid plate is a specialized cell culture tool designed to grow and maintain three-dimensional (3D) cell spheroids. These spheroids provide a more physiologically relevant model compared to traditional two-dimensional (2D) cell cultures, as they better mimic the complex cell-cell and cell-matrix interactions found in vivo.

Fig.1 Schematic diagram of the toxicity assay of a 3D hanging spheroid plate.¹

Main Features of the 3D Hanging Spheroid Plate:

• Hanging drop design
• Individual Wells
• Transparent construction
• Compatibility

3D Hanging Spheroid Plate-based Cytotoxicity Assay at Creative Biolabs

Our 3D hanging spheroid plate cytotoxicity assay service involves the use of advanced cell culture techniques to create and maintain 3D spheroids. These spheroids are then subjected to cytotoxic compounds to assess their effect on cell viability. We provide our clients with comprehensive and reliable results, from the construction of 3D suspended spheroid plates to the final data analysis and delivery.

Display Results

Here we present an important result of the CAR T cytotoxicity assay using three-dimensional suspended spheroid plates. These findings will help you a better understanding of our 3D hanging spheroid plate cytotoxicity assay service.

Applications of 3D Hanging Spheroid Plate

The 3D hanging spheroid plate is a versatile and powerful tool that significantly enhances the ability to model complex biological systems and diseases. Its applications span from basic research to drug discovery and personalized medicine, making it an essential resource for advancing biomedical research and therapeutic development. Here are some of the key applications related to 3D hanging spheroid plate:

As a novel technology, 3D hanging spheroid plates bring new possibilities for the toxicity detection of CAR-T cell therapy. If you are interested in this method, you can contact us directly and our CAR experts are available around the clock.

Reference

1. Chen, Zhenzhong et al. "3D hanging spheroid plate for high-throughput CAR T cell cytotoxicity assay." Journal of nanobiotechnology. (2022) 20,1 30.