Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsTo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
EXPLORE MORE HighlightsGet a real taste and understanding of the business and culture of one of the world's great research-based cellular and gene therapy discovery and development companies.
EXPLORE MOREAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
The split, universal, and programmable (SUPRA) CAR system is a two-component receptor system consisting of a universal receptor with leucine zipper adaptor (zipCAR) on T cells and a separate scFv with leucine zipper adaptor (zipFv) molecule targeting specific antigens. This split "lock-key" structure of SUPRA CAR with leucine zipper adaptors was desighed to enhance the flexibility and controllability of CARs, which has several clinically relevant advantages over a rigid CAR system:
• Antigen targets of one set of zipCAR T cells can be switched, expanded and combined without further modification of the CAR T cells.
• The activities and toxicities of SUPRA CAR T cells can be controlled and fine-tuned.
• Signaling domains and effector cell types can be changed and combined.
Creative Biolabs provides customized SUPRA design and construction services. Please contact us for more detailed information.
There are currently no customer reviews or questions for A ZipCAR [BZip-41BB-CD3ζ], with a CAR Adaptor [Anti-GPC3 Antibody scFv(2E10)-AZip], a SUPRA CAR System (CAR-NR-ZP950). Click the button below to contact us or submit your feedback about this product.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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