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Anti-AP T cell receptor (NB1 Y57Abeta), pCDTCR1 (TCR-YC0098)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-AP T cell receptor (TCR) is constructed for the engineering of T cell to target Acid phosphatase (SQLLNAKYL) restricted by H2-Dᵇ. The T cells are genetically modified through transduction with a lentiviral vector expressing AP-specific T cell receptor.

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Details

  • Target
  • AP
  • Target Species
  • Plasmodium berghei ANKA
  • Epitope
  • SQLLNAKYL
  • Format
  • Non-Modified TCR
  • Allele
  • H2-Dᵇ
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~ 8 kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • NB1 Y57Abeta
  • Host Species
  • Mouse

Target

  • Introduction
  • Acid phosphatase is a ubiquitous lysosomal enzyme that hydrolyses organic phosphates at an acid pH. Although the postpuberteral prostatic epithelial cell contains a uniquely high concentration of acid phosphatase, cellular components of bone, spleen, kidney, liver, intestine, and blood also contain this enzyme.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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