Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
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EXPLORE MOREAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
rRL-6-CH2OH was shown to trigger MAIT cell activation in an MR1-dependent manner, and it displayed the strongest potency in activating MAIT cells among three structurally related compounds. Thus, the increased MAIT TCR affinity for the E. coli–treated hbMR1 sample correlates with the presence of this ribityl moiety. The TCR recognizes reduced 6-(hydroxymethyl)-8-(1-D-ribityl)lumazine in the context of human MR1.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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