Creative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
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EXPLORE MORE HighlightsUse the resources in our library to help you understand your options and make critical decisions for your study. We offer oncolytic virus, CAR-T, and dendritic cell related documents, as well as newsletter. If you don't find the answers you're looking for, contact us for additional assistance.
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The integration of synthetic antigen receptors into immune cells has emerged as a powerful therapeutic strategy for treating various diseases, with T cells engineered to express chimeric antigen receptors (CAR) being a notable example for targeted cancer therapy. However, in addition to T lymphocytes, B lymphocytes have also shown promise as immune cells that can be genetically engineered for therapeutic purposes. One such approach involves using CAR-B cells to deliver monoclonal antibodies to tumor sites by targeting specific tumor-associated antigens (TAA).
Creative Biolabs has established a novel chimeric B cell receptors (CBCR) cell platform based on immortalized B cells to investigate the potential of CBCRs as a vehicle for adoptive immune cell therapies. Immortalized B cells are genomically modified with the Anti-CD123 CBCR vector (Cat.# XS-0323-ZP28). The expression of CBCR is then detected to confirm the precise integration of the anti-CD123 CBCR into the appropriate locus of the immortalized B cells.
There are currently no customer reviews or questions for Anti-CD123 (XP28 scFv-CD28TM-CD79β) CBCR, Immortalized B Cells (XS-0323-ZP884). Click the button below to contact us or submit your feedback about this product.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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