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Anti-Peptide YQY T cell receptor (3A/115), pCDTCR1 (TCR-YC0975)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-Peptide YQY T cell receptor (TCR) is constructed for the engineering of T cell to target Peptide YQY (YQYTFPDFLY) restricted by HLA-A*24:02. The T cells are genetically modified through transduction with a lentiviral vector expressing Peptide YQY-specific T cell receptor.

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Details

  • Target
  • Peptide YQY
  • Epitope
  • YQYTFPDFLY
  • Format
  • Non-Modified TCR
  • Allele
  • HLA-A*24:02
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~ 8 kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • 3A/115
  • Host Species
  • Human

Target

  • Introduction
  • Insulin-induced gene 1 (INSIG1) regulates sterol synthesis by mediating the activation of sterol regulatory element-binding protein (SREBP) and the degradation of the HMG-CoA reductase (HMGCR). INSIG1 is up-regulated during HIV-1 infection.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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