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Anti-RELA DNA-encoded mAb (DMAb), pVAX1 (DMAb-1971-WJ)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-RELA DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

  • Target
  • RELA
  • Vector Name
  • pVAX1
  • Vector Description
  • pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.
  • Vector Promoter
  • CMV
  • Vector Tag or Fusion
  • Untagged
  • Delivery Method
  • Transfection
  • Cloning Method
  • Restriction Enzyme ⁄ MCS
  • Constitutive or Inducible System
  • Constitutive
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.
  • Background
  • DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

  • Entrez Gene ID
  • 5970
Sub CAT. DMAb Clone DMAb Host Target Species DMAb Isotype DMAb Immunogen  
DMAb-1972-WJ 112A1021 Mouse IgG1, κ Synthetic peptide corresponding to amino acids 526-539 (GLLSGDEDFSSIAD) of human NF-kB (p65) protein
DMAb-1973-WJ 14H2 Mouse IgG1 NFkappaB p65 Mouse monoclonal antibody detects endogenous p65 proteins (~65KD)
DMAb-1455-WJ 4H211 Mouse IgG1, κ Synthetic peptide corresponding to amino acids 526-539 of human NF-kB (p65) protein
DMAb-626-YC 7G6 Mouse Human IgG Recombinant human NFKB p65
DMAb-0509-LY 8G3 Mouse Human IgG, λ RELA (NP_068810, 432 a.a. ~ 505 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: GEGTLSEALL QLQFDDEDLG ALLGNSTDPA VFTDLASVDN SEFQQLLNQG IPVAPHTTEP MLMEYPEAIT RLVT
DMAb-1978-WJ 93H1 Rabbit IgG
DMAb-1979-WJ D14E12 Rabbit IgG
DMAb-1980-WJ E379 Rabbit IgG
DMAb-1983-WJ L8F6 Mouse IgG2b
DMAb-1993-WJ 14G10A21 Mouse IgG2b, κ Partial human NF-κB p65 recombinant protein (451-551 aa)
DMAb-1995-WJ 2A12A7 Mouse IgG2a Recombinant protein (~175 amino acids) from the C-terminal portion of human NF-kappa-B (p65)
DMAb-1458-WJ 2Q2254 Mouse Human IgG3 Peptide corresponding to human p65 coupled to BSA
DMAb-1998-WJ 340C1a Mouse Human IgG1 RELA antibody was raised in mouse using recombinant Human V-Rel Reticuloendotheliosis Viral Oncogene Homolog A,Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3, P65 (Avian)
DMAb-2003-WJ 5G6 Mouse NFkappaB p65 Mouse monoclonal antibody detects endogenous p65 proteins
DMAb-1215-WJ 6H7 Mouse IgG1
DMAb-0137-YJ 7F1 Mouse IgG2b
DMAb-2006-WJ 9B4 Mouse IgG Synthetic Peptide
DMAb-2007-WJ 9C4 Mouse IgG Recombinant Protein
DMAb-2009-WJ A-12 Mouse
DMAb-2010-WJ BV706 Mouse IgG1
DMAb-2011-WJ C22B4 Rabbit IgG
DMAb-2012-WJ D2S3J Rabbit
DMAb-2013-WJ E1Z1T Mouse
DMAb-1622-WJ E-5 Mouse
DMAb-2016-WJ F-6 Mouse
DMAb-0130-CN G-8 Mouse
DMAb-2018-WJ J144-460 Mouse Human IgG1, κ Phosphorylated Human or Mouse NF-κB p65 Peptide
DMAb-2019-WJ NF-12 Mouse IgG1 Recombinant mouse NF-kB p65 fragment (C-terminal 151 aa)
DMAb-2021-WJ S-8 Mouse IgG1 NFkB p65 antibody was raised in Mouse using synthetic peptide from human NFkB as the immunogen

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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