Biotinylated Human CEACAM-5 CAR Detection Reagent, His,Avitag™ (CARD-LX160)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Evaluating CAR expression is an essential step in the production of CAR-T cells. Creative biolabs provides several detection reagents which are uniquely suitable for evaluation of CAR expression. Biotinylated Human CEACAM-5 CAR Detection Reagent, His,Avitag™ is a special detection reagent which is used to detect Human CEACAM-5 CAR related to the study of urachal cancer.

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Specifications

Target
CEACAM5

Application
FC, ELISA

Purity
>90%

Endotoxin Level
Less than 1.0 EU per μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Application Notes
The optimal working dilutions should be determined by the end user.

Diseases
urachal cancer

Molecular Characterization
It contains AA Lys 35 - Ala 685 (Accession # P06731-1).

Conjugation
Biotinylated

Size
200ug

Formulation
Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM Potassium glutamate, pH7.5. Normally trehalose is added as protectant before lyophilization.

Expression
Human HEK293 cells

Host Species
Human

Species Reactivity
Human

Form
lyophilized

Target

Target Introduction
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.

Target Alternative Names
CEACAM-5

UniProt ID
P06731-1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.