Human FAP CAR Detection Reagent, His Tag (FITC) (XS-0923-LX26)

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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

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Specifications

Target
FAP

Organism
Human

Application
Used for evaluating CAR expression.

Purity
>90%

Endotoxin Level
Less than 1.0 EU FITCr μg by the LAL method.

Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please protect from light and avoid repeated freeze-thaw cycles.

Shelf-Life
Stable as supplied until expiry date on label.

Application Notes
This product is recommended for FC application, and the optimal working dilutions should be determined by the end user.

Diseases
Lung malignancy

Molecular Characterization
The CAR detection reagent contains AA Leu 26 - Asp 760 of Human FAP.

Conjugation
FITC

Size
25 tests; 100 tests

Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Expression
HEK293 cell

Host Species
Human

Species Reactivity
Human

Form
Lyophilized

Target

Target Introduction
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelialmesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target Alternative Names
fibroblast activation protein alpha

Entrez Gene ID
2191

UniProt ID
P00533-1

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Human FAP CAR Detection Reagent, His Tag (FITC) (XS-0923-LX26)

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Specifications

Target

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