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FGFR1

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The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A fulllength representative protein consists of an extracellular region, composed of three immunoglobulinlike domains, a single hydrophobic membranespanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, JacksonWeiss syndrome, AntleyBixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP9917 Anti-FGFR1 (N6G11) h(CD28-CD3ζ) CAR, pCDCAR1 Human N6G11 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9921 Anti-FGFR1 (XHM415) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM415 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9922 Anti-FGFR1 (XHM415) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM415 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9923 Anti-FGFR1 (XHM416) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM416 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9924 Anti-FGFR1 (XHM416) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM416 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9925 Anti-FGFR1 (XHM417) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM417 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9926 Anti-FGFR1 (XHM417) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM417 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9927 Anti-FGFR1 (XHM418) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM418 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9928 Anti-FGFR1 (XHM418) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM418 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9929 Anti-FGFR1 (1XHM419) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM419 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9930 Anti-FGFR1 (1XHM419) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM419 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9931 Anti-FGFR1 (XHM420) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM420 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9932 Anti-FGFR1 (XHM420) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM420 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9933 Anti-FGFR1 (XHM421) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM421 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9934 Anti-FGFR1 (XHM421) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM421 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9935 Anti-FGFR1 (XHM422) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM422 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9936 Anti-FGFR1 (XHM422) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM422 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9937 Anti-FGFR1 (XHM423) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM423 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9938 Anti-FGFR1 (XHM423) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM423 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9939 Anti-FGFR1 (XHM424) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM424 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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