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ITGAV

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
  • AbTCR Vector Products

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CAT Product Name Target Species Antibody Clone Fab-Host Animal Vector Type Targeting Cell Type Inquiry & Datasheet
XS-0722-ZP4118 Anti-ITGAV X CD3 BsAb Secreting T Cell Redirecting Vector (ITGAVxCD3) Human T Cells   Add to Cart   Datasheet
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