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All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant. The general structure of phosphatidylglycerol consists of a L-glycerol 3-phosphate backbone ester-bonded to either saturated or unsaturated fatty acids on carbons 1 and 2. The head group substituent glycerol is bonded through a phosphomonoester. It is the precursor of surfactant and its presence (> 0.3) in the amniotic fluid of the newborn indicates fetal lung maturity. Approximately 98% of alveolar wall surface area is due to the presence of type I cells, with type II cells producing pulmonary surfactant covering around 2% of the alveolar walls. Once surfactant is secreted by the type II cells, it must be spread over the remaining type I cellular surface area. Phosphatidylglycerol is thought to be important in spreading of surfactant over the Type I cellular surface area. The major surfactant deficiency in premature infants relates to the lack of phosphatidylglycerol, even though it comprises less than 5% of pulmonary surfactant phospholipids. It is synthesized by head group exchange of a phosphatidylcholine enriched phospholipid using the enzyme phospholipase D.

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CAT Product Name Target Species TCR Clone Host Species Epitope Allele Vector Type Inquiry & Datasheet
TCR-YC0976 Human anti-PG T cell receptor (BC8B), pCDTCR1 BC8B Human Phosphatidylglycerol human CD1b Lentiviral vector   Add to Cart   Datasheet
TCR-YC0977 Human anti-PG T cell receptor (PG10), pCDTCR1 E. coli PG10 Human L-α-phosphatidylglycerol (sodium salt) human CD1b Lentiviral vector   Add to Cart   Datasheet
TCR-YC0978 Human anti-PG T cell receptor (PG90), pCDTCR1 E. coli PG90 Human L-α-phosphatidylglycerol (sodium salt) human CD1b Lentiviral vector   Add to Cart   Datasheet
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