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PTPN13

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PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-0320ZP1753 Anti-PTPN13 (BD32) h(CD28-CD3ζ) CAR, pCDCAR1 Human BD32 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1754 Anti-PTPN13 (BD32) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human BD32 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1755 Anti-PTPN13 (CBYC-P779) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBYC-P779 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1756 Anti-PTPN13 (CBYC-P779) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBYC-P779 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1757 Anti-PTPN13 (D6D1H) h(CD28-CD3ζ) CAR, pCDCAR1 Human D6D1H Rabbit scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1758 Anti-PTPN13 (D6D1H) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human D6D1H Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1759 Anti-PTPN13 (4F6) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4F6 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1760 Anti-PTPN13 (4F6) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 4F6 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1761 Anti-PTPN13 (1A6) h(CD28-CD3ζ) CAR, pCDCAR1 Human 1A6 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0320ZP1762 Anti-PTPN13 (1A6) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 1A6 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
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