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SLC7A11

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a member of a heteromeric, sodiumindependent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcomaassociated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-0120ZP2331 Anti-SLC7A11 (HAb18) h(CD28-CD3ζ) CAR, pCDCAR1 Human HAb18 Mouse scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2332 Anti-SLC7A11 (HAb18) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human HAb18 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2333 Anti-SLC7A11 (D2M7A) h(CD28-CD3ζ) CAR, pCDCAR1 Human D2M7A Rabbit scFv-CD28-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
CAR-0120ZP2334 Anti-SLC7A11 (D2M7A) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human D2M7A Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T Cell   Add to Cart   Datasheet
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