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STAT3

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The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantileonset multisystem autoimmune disease and hyperimmunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-ZP9523 Anti-STAT3 (XHM470) h(CD28-CD3ζ) CAR, pCDCAR1 Human XHM470 Camel scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9524 Anti-STAT3 (XHM470) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human XHM470 Camel scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9525 Anti-STAT3 (ST3G12) h(CD28-CD3ζ) CAR, pCDCAR1 Human ST3G12 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9526 Anti-STAT3 (ST3G12) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human ST3G12 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9527 Anti-STAT3 (ST1A5) h(CD28-CD3ζ) CAR, pCDCAR1 Human ST1A5 Human scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9528 Anti-STAT3 (ST1A5) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human ST1A5 Human scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9529 Anti-STAT3 (CBACN-671) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBACN-671 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9530 Anti-STAT3 (CBACN-671) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBACN-671 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9531 Anti-STAT3 (CBACN-529) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBACN-529 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9532 Anti-STAT3 (CBACN-529) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBACN-529 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9533 Anti-STAT3 (CBACN-530) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBACN-530 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9534 Anti-STAT3 (CBACN-530) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBACN-530 Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9535 Anti-STAT3 (TH225DS) h(CD28-CD3ζ) CAR, pCDCAR1 Human TH225DS Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9536 Anti-STAT3 (TH225DS) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human TH225DS Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9537 Anti-STAT3 (DS3427AB) h(CD28-CD3ζ) CAR, pCDCAR1 Human DS3427AB Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9538 Anti-STAT3 (DS3427AB) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human DS3427AB Rabbit scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9539 Anti-STAT3 (CBDH2800) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBDH2800 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9540 Anti-STAT3 (CBDH2800) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human CBDH2800 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9541 Anti-STAT3 (7D1) h(CD28-CD3ζ) CAR, pCDCAR1 Human 7D1 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-ZP9542 Anti-STAT3 (7D1) h(4-1BB-CD3ζ) CAR, pCDCAR1 Human 7D1 Mouse scFv-4-1BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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