This is an aptamer development services to screening aptamers binds to the BOLL with an affinity of 1nM~1μM.
Target Category | Protein |
Target | BOLL |
Alternative Names | Boule Homolog, RNA Binding Protein; BOULE; Boule-Like RNA Binding Protein; Protein Boule-Like; Bol (Drosophila Boule Homolog)-Like; Bol, Boule-Like (Drosophila) ; Bol, Boule-Like; BOLL |
Gene ID | 66037 |
UniProt ID | Q8N9W6 |
Target Overview | This gene belongs to the DAZ gene family required for germ cell development. It encodes an RNA-binding protein which is more similar to Drosophila Boule than to human proteins encoded by genes DAZ (deleted in azoospermia) or DAZL (deleted in azoospermia-like). Loss of this gene function results in the absence of sperm in semen (azoospermia). Histological studies demonstrated that the primary defect is at the meiotic G2/M transition. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
Chemical Modification | N/A |
Type | DNA |
Length | 20-80 nt |
Affinity (Kd) | 1nM~1μM |
Binding Conditions/Buffer | PBS; buffer system with Serum; other |