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Influenza virus-like particles (H3N2 VLPs) (CAT#: VLP-036YF)

Datasheet
Recombinant Influenza virus M1 virus-like particles (H3N2 M1 VLPs) are produced in Baculovirus/Insect cell expression system, assembled with structural proteins (HA, NA, M1 and M2). VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. H3N2 M1 VLPs can be used in the development of Influenza virus diagnostics and in vaccine development and R&D (including use as an immunogen).

Product Specifications

  • Structural Proteins
  • Structural proteins (HA, NA, M1 and M2)
  • Expression Systems
  • Insect cell (Sf9) expression system
  • Form
  • Liquid
  • Alternative Names
  • Influenza; Influenza virus-like particles; H3N2; H3N2 virus-like particles; Influenza VLPs; H3N2 VLPs; virus-like particles; VLPs
  • Storage
  • Store at -80°C long term. Avoid repeated freeze/thaw cycles.

Virus Background

  • Virus Family
  • Orthomyxoviridae
  • Virus Species
  • Influenza virus
  • Virus Overview
  • Influenza A virus causes influenza in birds and some mammals, and is the only species of the genus Alphainfluenzavirus of the virus family Orthomyxoviridae.Influenza A viruses are negative-sense, single-stranded, segmented RNA viruses. The several subtypes are labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 18 different known H antigens (H1 to H18) and 11 different known N antigens (N1 to N11).Each virus subtype has mutated into a variety of strains with differing pathogenic profiles; some are pathogenic to one species but not others, some are pathogenic to multiple species.
  • Virus Structure
  • Enveloped, negative-sense, single-stranded RNA virus
  • Related Disease
  • Influenza

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