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Hepatitis B Virus-like Particles (HBV VLPs-HBc) (CAT#: VLP-008YF)

Datasheet
Recombinant Hepatitis B Virus-like Particles (HBV VLPs) are produced in mammalian HEK293 human cells, assembled with core antigens. VLP is mimicking the native 3D structure of viruses which can elicit strong immune responses. However, VLPs lack viral genomic material which makes them non-infectious, unable to replicate and enhance the safety during manufacture and administration. HBV VLPs can be used in the development of HBV diagnostics and in vaccine development and R&D (including use as an immunogen).

Product Specifications

  • Expression Systems
  • HEK293 (please specify if other expression system is needed)
  • Form
  • Liquid
  • Alternative Names
  • Hepatitis B Virus; HBV; Hepatitis B Virus VLP; HBV VLP; VLP; Virus-like particle
  • Storage
  • Store at -80 °C long term. Avoid repeated freeze/thaw cycles.

Virus Background

  • Virus Family
  • Hepadnaviridae
  • Virus Species
  • Hepatitis B Virus
  • Virus Overview
  • Hepatitis B virus (HBV), is a partially double-stranded DNA virus, a species of the genus Orthohepadnavirus and a member of the Hepadnaviridae family of viruses. This virus causes the disease hepatitis B. In addition to causing hepatitis, infection with HBV can lead to cirrhosis and hepatocellular carcinoma. It consists of HBsAg, HBcAg, DNA polymerase and HBx. Hepatitis B surface antigen (HBsAg) was the first hepatitis B virus protein to be discovered. It consists of small (S), medium (M) and large (L) protein.
  • Virus Structure
  • Enveloped, double-stranded DNA virus
  • Related Disease
  • Hepatitis B

Customer reviews and Q&As    

Customer Review

Enhanced immune response capacity after modification

The immune response capacity of HBV VLPs was enhanced after high glycosylation modification.
2022-12-07

All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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