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Magic™ Antibody Discovery - Human B7-1 / CD80 (35-242) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0959F)

Datasheet
This membrane protein is Human B7-1 / CD80 (35-242). It has been tested in SDS-PAGE, HPLC, ELISA, BLI, SPR, FACS. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • B7-1 / CD80
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 50.0 kDa. The protein migrates as 65-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Val 35 - Asn 242 (Accession # NP_005182.1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, HPLC, ELISA, BLI, SPR, FACS
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
    >95% as determined by SEC-HPLC.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • B7-1 / CD80
  • Full Name
  • CD80 molecule
  • Introduction
  • The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.
  • Alternative Names
  • B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1; T-lymphocyte activation antigen CD80; B-lymphocyte activation antigen B7; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CTLA-4 counter-receptor B7.1; activation B7-1 antigen; costimulatory factor CD80; costimulatory molecule variant IgV-CD80

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