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Magic™ Membrane Protein Human EPHA5 (EPH receptor A5) Expressed in NS0 for Antibody Discovery, Partial (56-573aa) (CAT#: MPX0415K)

Datasheet
This product is a 58.4 kDa Human EPHA5 membrane protein expressed in NS0. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • EPHA5
  • Protein Length
  • Partial (56-573aa)
  • Protein Class
  • Transferase
  • Molecular Weight
  • 58.4 kDa
  • TMD
  • 1
  • Sequence
  • SPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ
    VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKET
    FNMYYFESDDQNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVR
    DVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHLAVFPDTITGA
    DSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
    TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPP
    TMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS
    HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDL
    SPGARQYVSVNVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIIL
    EYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQIRARTAAGYGV
    FSRRFEFETTPVFAASSDQSQIP

Product Description

  • Activity
  • Yes
  • Expression Systems
  • NS0
  • Tag
  • 6xHis tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Reconstitute at 100 μg/mL in sterile PBS.
  • Endotoxin
  • <0.01 EU per 1 μg of the protein by the LAL method.
  • Purity
  • >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
  • Buffer
  • Lyophilized from a 0.2 μm filtered solution in PBS.

Target

  • Target Protein
  • EPHA5
  • Full Name
  • EPH receptor A5
  • Introduction
  • This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Alternative Names
  • EPHA5; EK7; CEK7; EHK1; HEK7; EHK-1; TYRO4; ephrin type-A receptor 5; EPH homology kinase 1; EPH-like kinase 7; brain-specific kinase; epididymis secretory sperm binding protein; receptor protein-tyrosine kinase HEK7; tyrosine-protein kinase receptor EHK-1; EPH receptor A5

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