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Magic™ Antibody Discovery - Human CD200 / OX-2 (31-232) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP1222F)

Datasheet
This membrane protein is Human CD200 / OX-2 (31-232). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CD200 / OX-2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 48.6 kDa. The protein migrates as 55-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Gln 31 - Gly 232 (Accession # AAH22522).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CD200 / OX-2
  • Full Name
  • CD200 molecule
  • Introduction
  • This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • MRC; MOX1; MOX2; OX-2; OX-2 membrane glycoprotein; CD200 antigen; antigen identified by monoclonal antibody MRC OX-2

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