Close
Close

Magic™ Antibody Discovery - Human Complement Component C2 (21-752) Membrane Protein, Partial, -His tag (CAT#: MP1069F)

Datasheet
This membrane protein is Human Complement Component C2 (21-752). It has been tested in SDS-PAGE, SEC-SEC-MALS. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • Complement Component C2
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 83.0 kDa. The protein migrates as 95-115 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
  • Sequence
  • AA Ala 21 - Leu 752 (Accession # P06681-1).

Product Description

  • Application
  • SDS-PAGE, SEC-SEC-MALS
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
    >90% as determined by SEC-MALS.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • Complement Component C2
  • Full Name
  • complement C2
  • Introduction
  • Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.
  • Alternative Names
  • CO2; ARMD14; complement C2; C3/C5 convertase; complement component 2; complement component C2

Customer reviews and Q&As    

Related Products
Online Inquiry
CONTACT US
USA:
Europe:
Germany:
Call us at:
USA:
UK:
Germany:
Fax:
Email:
Our customer service representatives are available 24 hours a day, 7 days a week. Contact Us
© 2024 Creative Biolabs. | Contact Us