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Magic™ Membrane Protein Human SPAG4 (Sperm associated antigen 4) Full Length (CAT#: MPC3100K) Made to Order

Datasheet
This product is a made-to-order Human SPAG4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • SPAG4
  • Protein Length
  • Full length
  • Protein Class
  • Receptor
  • TMD
  • 2
  • Sequence
  • MRRSSRPGSASSSRKHTPNFFSENSSMSITSEDSKGLRSAEPGPGEPEGR
    RARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQTACGAATVRGGA
    SEPTGSPVVSEEPLDLLPTLDLRQEMPPPRVFKSFLSLLFQGLSVLLSLA
    GDVLVSMYREVCSIRFLFTAVSLLSLFLSAFWLGLLYLVSPLENEPKEML
    TLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSERVAKLVFQRLN
    EDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTV
    ILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGAN
    SAPRDFAVFGLQVYDETEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVK
    IQILSNWGHPRFTCLYRVRAHGVRTSEGAEGSAQGPH

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • SPAG4
  • Full Name
  • Sperm associated antigen 4
  • Introduction
  • The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers surrounding the axoneme in the midpiece and principal piece and the fibrous sheath surrounding the outer dense fibers in the principal piece of the tail. Defects in these structures are associated with abnormal tail morphology, reduced sperm motility, and infertility. In the rat, the protein encoded by this gene associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development. Alternative splicing results in multiple transcript variants encoding different isoforms.
  • Alternative Names
  • SPAG4; SUN4; CT127; sperm-associated antigen 4 protein; SUN domain-containing protein 4; Sad1 and UNC84 domain containing 4; acrosomal protein ACR55; cancer/testis antigen 127; outer dense fiber-associated protein SPAG4; sperm tail protein; Sperm associated antigen 4

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