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Magic™ Antibody Discovery - Human CXCR4 / CD184 (1-46) Membrane Protein, Partial, hIgG1 Fc- tag (CAT#: MP1087F)

Datasheet
This membrane protein is Human CXCR4 / CD184 (1-46). It has been tested in SDS-PAGE. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CXCR4 / CD184
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 32.3 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Met 1 - Ser 46 (Accession # AAH20968.1).

Product Description

  • Application
  • SDS-PAGE
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the N-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • CXCR4 / CD184
  • Full Name
  • C-X-C motif chemokine receptor 4
  • Introduction
  • This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  • Alternative Names
  • CXCR4, chemokine (C-X-C motif) receptor 4, chemokine (C X C motif), receptor 4 (fusin), C-X-C chemokine receptor type 4, CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R, CXC-R4, CXCR-4, CD184 antigen, SDF-1 receptor, neuropeptide Y receptor Y3, seven transmembrane helix receptor, stromal cell-derived factor 1 receptor, lipopolysaccharide-associated protein 3, seven-transmembrane-segment receptor, spleen, leukocyte-derived seven transmembrane domain receptor, leukocyte-derived seven-transmembrane-domain receptor, FB22, LAP3, LCR1, WHIM, NPYRL,

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