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Magic™ Antibody Discovery - Human G-CSF R / CD114 (25-621) Membrane Protein, Partial, -hIgG1 Fc tag (CAT#: MP0176F)

Datasheet
This membrane protein is Human G-CSF R / CD114 (25-621). It has been tested in SDS-PAGE, ELISA. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • G-CSF R / CD114
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 92.7 kDa. The protein migrates as 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Glu 25 - Pro 621 (Accession # NP_000751.1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, ELISA
  • Expression Systems
  • HEK293
  • Tag
  • Human IgG1 Fc tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >95% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • G-CSF R / CD114
  • Full Name
  • colony stimulating factor 3 receptor
  • Introduction
  • The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
  • Alternative Names
  • SCN7; CD114; GCSFR; granulocyte colony-stimulating factor receptor; CD114 antigen; G-CSF receptor; G-CSF-R; colony stimulating factor 3 receptor (granulocyte)

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