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Magic™ Antibody Discovery - Human RIB / ACVR1B (24-126) Membrane Protein, Partial, -His tag (CAT#: MP0920F)

Datasheet
This membrane protein is Human RIB / ACVR1B (1-140). It has been tested in SDS-PAGE, BLI. We provide this protein to facilitate your membrane protein antibody discovery and development.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • RIB / ACVR1B
  • Protein Length
  • ECD
  • Molecular Weight
  • The protein has a calculated MW of 13.3 kDa. The protein migrates as 16-22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Sequence
  • AA Ser 24 - Glu 126 (Accession # P36896-1).

Product Description

  • Activity
  • Yes
  • Application
  • SDS-PAGE, BLI
  • Expression Systems
  • HEK293
  • Tag
  • His tag at the C-terminus
  • Protein Format
  • Soluble
  • Reconstitution
  • Please see Certificate of Analysis for specific instructions.
  • Endotoxin
  • <1.0 EU/μg by the LAL method
  • Purity
  • >90% as determined by SDS-PAGE.
  • Buffer
  • Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Target

  • Target Protein
  • RIB / ACVR1B
  • Full Name
  • activin A receptor type 1B
  • Introduction
  • This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • ALK4; SKR2; ACTRIB; ACVRLK4; activin receptor type-1B; activin A receptor, type IB; activin A receptor, type II-like kinase 4; activin receptor-like kinase 4; serine/threonine-protein kinase receptor R2
  • Gene ID
  • 91

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