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Magic™ Membrane Protein Human APLP2 (Amyloid beta precursor like protein 2) Full Length (CAT#: MPC1608K) Made to Order

Datasheet
This product is a 86.9 kDa Human APLP2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • APLP2
  • Protein Length
  • Full length
  • Protein Class
  • Protease inhibitor
  • Molecular Weight
  • 86.9 kDa
  • TMD
  • 1
  • Sequence
  • MAATGTAAAAATGRLLLLLLVGLTAPALALAGYIEALAANAGTGFAVAEP
    QIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQI
    TNVMEANQRVSIDNWCRRDKKQCKSRFVTPFKCLVGEFVSDVLLVPEKCQ
    FFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEY
    VCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFT
    EAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDK
    EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNF
    ESEDYCMAVCKAMIPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIR
    HRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQ
    QLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAE
    NKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKV
    PYVAQEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFH
    PFHPFPALPENEDTQPELYHPMKKGSGVGEQDGGLIGAEEKVINSKNKVD
    ENMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLV
    IAVAIATVIVISLVMLRKRQYGTISHGIVEVDPMLTPEERHLNKMQNHGY
    ENPTYKYLEQMQI

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • APLP2
  • Full Name
  • Amyloid beta precursor like protein 2
  • Introduction
  • This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
  • Alternative Names
  • APLP2; APPH; APPL2; CDEBP; APLP-2; amyloid-like protein 2; CDEI box-binding protein; amyloid beta (A4) precursor-like protein 2; amyloid precursor protein homolog HSD-2; testicular tissue protein Li 23; Amyloid beta precursor like protein 2

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