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Magic™ Membrane Protein Human PTPRE (Protein tyrosine phosphatase receptor type E) Full Length (CAT#: MPC2083K) Made to Order

Datasheet
This product is a 80.6 kDa Human PTPRE membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • PTPRE
  • Protein Length
  • Full length
  • Protein Class
  • Protein phosphatase
  • Molecular Weight
  • 80.6 kDa
  • TMD
  • 1
  • Sequence
  • MEPLCPLLLVGFSLPLARALRGNETTADSNETTTTSGPPDPGASQPLLAW
    LLLPLLLLLLVLLLAAYFFRFRKQRKAVVSTSDKKMPNGILEEQEQQRVM
    LLSRSPSGPKKYFPIPVEHLEEEIRIRSADDCKQFREEFNSLPSGHIQGT
    FELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDGYKE
    KNKFIAAQGPKQETVNDFWRMVWEQKSATIVMLTNLKERKEEKCHQYWPD
    QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQLPDGCKAPRLVSQLHFTS
    WPDFGVPFTPIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDA
    MMAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDT
    ELDVSSLEKHLQTMHGTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPA
    NMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFIDGYRQKDYFIATQ
    GPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTEGSVTHGE
    ITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIGI
    PAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERV
    KAEGLLDVFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • PTPRE
  • Full Name
  • Protein tyrosine phosphatase receptor type E
  • Introduction
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.
  • Alternative Names
  • PTPRE; PTPE; HPTPE; R-PTP-EPSILON; receptor-type tyrosine-protein phosphatase epsilon; protein tyrosine phosphatase, receptor type, epsilon polypeptide; Protein tyrosine phosphatase receptor type E

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