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Magic™ Membrane Protein Human ASIC3 (Acid sensing ion channel subunit 3) Full Length (CAT#: MPC0403K) Made to Order

This product is a 58.9 kDa Human ASIC3 membrane protein expressed in Baculovirus/Insect expression system. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • ASIC3
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 58.9 kDa
  • TMD
  • 2
  • Sequence
  • MKPTSGPEEARRPASDIRVFASNCSMHGLGHVFGPGSLSLRRGMWAAAVV
    LSVATFLYQVAERVRYYREFHHQTALDERESHRLIFPAVTLCNINPLRRS
    RLTPNDLHWAGSALLGLDPAEHAAFLRALGRPPAPPGFMPSPTFDMAQLY
    ARAGHSLDDMLLDCRFRGQPCGPENFTTIFTRMGKCYTFNSGADGAELLT
    TTRGGMGNGLDIMLDVQQEEYLPVWRDNEETPFEVGIRVQIHSQEEPPII
    DQLGLGVSPGYQTFVSCQQQQLSFLPPPWGDCSSASLNPNYEPEPSDPLG
    SPSPSPSPPYTLMGCRLACETRYVARKCGCRMVYMPGDVPVCSPQQYKNC
    AHPAIDAMLRKDSCACPNPCASTRYAKELSMVRIPSRAAARFLARKLNRS
    EAYIAENVLALDIFFEALNYETVEQKKAYEMSELLGDIGGQMGLFIGASL
    LTILEILDYLCEVFRDKVLGYFWNRQHSQRHSSTNLLQEGLGSHRTQVPH
    LSLGPRPPTPPCAVTKTLSASHRTCYLVTQL

Product Description

  • Expression Systems
  • Baculovirus/Insect expression system
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • ASIC3
  • Full Name
  • Acid sensing ion channel subunit 3
  • Introduction
  • This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.
  • Alternative Names
  • ACCN3; TNaC1; DRASIC; SLNAC1; acid-sensing ion channel 3; acid sensing (proton gated) ion channel 3; amiloride-sensitive cation channel 3, testis; modulatory subunit of ASIC2a; neuronal amiloride-sensitive cation channel 3; proton-gated cation channel subunit; testis sodium channel 1; ASIC3; Acid sensing ion channel subunit 3

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