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Magic™ Membrane Protein Human CLRN1 (Clarin 1) Full Length (CAT#: MPC2522K) Made to Order

This product is a made-to-order Human CLRN1 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CLRN1
  • Protein Length
  • Full length
  • Protein Class
  • Transporter
  • TMD
  • 4
  • Sequence
  • MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNAS
    GQELDKFMGEMQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVN
    VILFSAILIVLTMVGTAFFMYNAFGKPFETLHGPLGLYLLSFISGSCGCL
    VMILFASEVKIHHLSEKIANYKEGTYVYKTQSEKYTTSFWVIFFCFFVHF
    LNGLLIRLAGFQFPFAKSKDAETTNVAADLMY

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements (Detergent, Liposome, Nanodisc, SMALPs, VLP)

Target

  • Target Protein
  • CLRN1
  • Full Name
  • Clarin 1
  • Introduction
  • This gene encodes a protein that contains a cytosolic N-terminus, multiple helical transmembrane domains, and an endoplasmic reticulum membrane retention signal, TKGH, in the C-terminus. The encoded protein may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIIa. Multiple transcript variants encoding distinct isoforms have been identified for this gene.
  • Alternative Names
  • CLRN1; RP61; USH3; USH3A; clarin-1; Usher syndrome type-3 protein; Clarin 1

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