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Magic™ Membrane Protein Human BMPR2 (Bone morphogenetic protein receptor type 2) Full Length (CAT#: MPC1755K) Made to Order

Datasheet
This product is a 115.2 kDa Human BMPR2 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • BMPR2
  • Protein Length
  • Full length
  • Protein Class
  • Transferase
  • Molecular Weight
  • 115.2 kDa
  • TMD
  • 1
  • Sequence
  • MTSSLQRPWRVPWLPWTILLVSTAAASQNQERLCAFKDPYQQDLGIGESR
    ISHENGTILCSKGSTCYGLWEKSKGDINLVKQGCWSHIGDPQECHYEECV
    VTTTPPSIQNGTYRFCCCSTDLCNVNFTENFPPPDTTPLSPPHSFNRDET
    IIIALASVSVLAVLIVALCFGYRMLTGDRKQGLHSMNMMEAAASEPSLDL
    DNLKLLELIGRGRYGAVYKGSLDERPVAVKVFSFANRQNFINEKNIYRVP
    LMEHDNIARFIVGDERVTADGRMEYLLVMEYYPNGSLCKYLSLHTSDWVS
    SCRLAHSVTRGLAYLHTELPRGDHYKPAISHRDLNSRNVLVKNDGTCVIS
    DFGLSMRLTGNRLVRPGEEDNAAISEVGTIRYMAPEVLEGAVNLRDCESA
    LKQVDMYALGLIYWEIFMRCTDLFPGESVPEYQMAFQTEVGNHPTFEDMQ
    VLVSREKQRPKFPEAWKENSLAVRSLKETIEDCWDQDAEARLTAQCAEER
    MAELMMIWERNKSVSPTVNPMSTAMQNERNLSHNRRVPKIGPYPDYSSSS
    YIEDSIHHTDSIVKNISSEHSMSSTPLTIGEKNRNSINYERQQAQARIPS
    PETSVTSLSTNTTTTNTTGLTPSTGMTTISEMPYPDETNLHTTNVAQSIG
    PTPVCLQLTEEDLETNKLDPKEVDKNLKESSDENLMEHSLKQFSGPDPLS
    STSSSLLYPLIKLAVEATGQQDFTQTANGQACLIPDVLPTQIYPLPKQQN
    LPKRPTSLPLNTKNSTKEPRLKFGSKHKSNLKQVETGVAKMNTINAAEPH
    VVTVTMNGVAGRNHSVNSHAATTQYANGTVLSGQTTNIVTHRAQEMLQNQ
    FIGEDTRLNINSSPDEHEPLLRREQQAGHDEGVLDRLVDRRERPLEGGRT
    NSNNNNSNPCSEQDVLAQGVPSTAADPGPSKPRRAQRPNSLDLSATNVLD
    GSSIQIGESTQDGKSGSGEKIKKRVKTPYSLKRWRPSTWVISTESLDCEV
    NNNGSNRAVHSKSSTAVYLAEGGTATTMVSKDIGMNCL

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • BMPR2
  • Full Name
  • Bone morphogenetic protein receptor type 2
  • Introduction
  • This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
  • Alternative Names
  • BMPR2; BMR2; PPH1; BMPR3; BRK-3; POVD1; T-ALK; BMPR-II; bone morphogenetic protein receptor type-2; BMP type II receptor; BMP type-2 receptor; bone morphogenetic protein receptor type II; bone morphogenetic protein receptor, type II (serine/threonine kinase); type II activin receptor-like kinase; type II receptor for bone morphogenetic protein-4; Bone morphogenetic protein receptor type 2

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