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Magic™ Membrane Protein Human CACNA1I (Calcium voltage-gated channel subunit alpha1 I) Full Length (CAT#: MPC0428K) Made to Order

This product is a 245.1 kDa Human CACNA1I membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CACNA1I
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 245.1 kDa
  • TMD
  • 24
  • Sequence
  • MAESASPPSSSAAAPAAEPGVTTEQPGPRSPPSSPPGLEEPLDGADPHVP
    HPDLAPIAFFCLRQTTSPRNWCIKMVCNPWFECVSMLVILLNCVTLGMYQ
    PCDDMDCLSDRCKILQVFDDFIFIFFAMEMVLKMVALGIFGKKCYLGDTW
    NRLDFFIVMAGMVEYSLDLQNINLSAIRTVRVLRPLKAINRVPSMRILVN
    LLLDTLPMLGNVLLLCFFVFFIFGIIGVQLWAGLLRNRCFLEENFTIQGD
    VALPPYYQPEEDDEMPFICSLSGDNGIMGCHEIPPLKEQGRECCLSKDDV
    YDFGAGRQDLNASGLCVNWNRYYNVCRTGSANPHKGAINFDNIGYAWIVI
    FQVITLEGWVEIMYYVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQ
    FSETKQREHRLMLEQRQRYLSSSTVASYAEPGDCYEEIFQYVCHILRKAK
    RRALGLYQALQSRRQALGPEAPAPAKPGPHAKEPRHYHGKTKGQGDEGRH
    LGSRHCQTLHGPASPGNDHSGRELCPQHSPLDATPHTLVQPIPATLASDP
    ASCPCCQHEDGRRPSGLGSTDSGQEGSGSGSSAGGEDEADGDGARSSEDG
    ASSELGKEEEEEEQADGAVWLCGDVWRETRAKLRGIVDSKYFNRGIMMAI
    LVNTVSMGIEHHEQPEELTNILEICNVVFTSMFALEMILKLAAFGLFDYL
    RNPYNIFDSIIVIISIWEIVGQADGGLSVLRTFRLLRVLKLVRFMPALRR
    QLVVLMKTMDNVATFCMLLMLFIFIFSILGMHIFGCKFSLRTDTGDTVPD
    RKNFDSLLWAIVTVFQILTQEDWNVVLYNGMASTSPWASLYFVALMTFGN
    YVLFNLLVAILVEGFQAEGDANRSYSDEDQSSSNIEEFDKLQEGLDSSGD
    PKLCPIPMTPNGHLDPSLPLGGHLGPAGAAGPAPRLSLQPDPMLVALGSR
    KSSVMSLGRMSYDQRSLSSSRSSYYGPWGRSAAWASRRSSWNSLKHKPPS
    AEHESLLSAERGGGARVCEVAADEGPPRAAPLHTPHAHHIHHGPHLAHRH
    RHHRRTLSLDNRDSVDLAELVPAVGAHPRAAWRAAGPAPGHEDCNGRMPS
    IAKDVFTKMGDRGDRGEDEEEIDYTLCFRVRKMIDVYKPDWCEVREDWSV
    YLFSPENRFRVLCQTIIAHKLFDYVVLAFIFLNCITIALERPQIEAGSTE
    RIFLTVSNYIFTAIFVGEMTLKVVSLGLYFGEQAYLRSSWNVLDGFLVFV
    SIIDIVVSLASAGGAKILGVLRVLRLLRTLRPLRVISRAPGLKLVVETLI
    SSLKPIGNIVLICCAFFIIFGILGVQLFKGKFYHCLGVDTRNITNRSDCM
    AANYRWVHHKYNFDNLGQALMSLFVLASKDGWVNIMYNGLDAVAVDQQPV
    TNHNPWMLLYFISFLLIVSFFVLNMFVGVVVENFHKCRQHQEAEEARRRE
    EKRLRRLEKKRRKAQRLPYYATYCHTRLLIHSMCTSHYLDIFITFIICLN
    VVTMSLEHYNQPTSLETALKYCNYMFTTVFVLEAVLKLVAFGLRRFFKDR
    WNQLDLAIVLLSVMGITLEEIEINAALPINPTIIRIMRVLRIARVLKLLK
    MATGMRALLDTVVQALPQVGNLGLLFMLLFFIYAALGVELFGKLVCNDEN
    PCEGMSRHATFENFGMAFLTLFQVSTGDNWNGIMKDTLRDCTHDERSCLS
    SLQFVSPLYFVSFVLTAQFVLINVVVAVLMKHLDDSNKEAQEDAEMDAEL
    ELEMAHGLGPGPRLPTGSPGAPGRGPGGAGGGGDTEGGLCRRCYSPAQEN
    LWLDSVSLIIKDSLEGELTIIDNLSGSIFHHYSSPAGCKKCHHDKQEVQL
    AETEAFSLNSDRSSSILLGDDLSLEDPTACPPGRKDSKGELDPPEPMRVG
    DLGECFFPLSSTAVSPDPENFLCEMEEIPFNPVRSWLKHDSSQAPPSPFS
    PDASSPLLPMPAEFFHPAVSASQKGPEKGTGTGTLPKIALQGSWASLRSP
    RVNCTLLRQATGSDTSLDASPSSSAGSLQTTLEDSLTLSDSPRRALGPPA
    PAPGPRAGLSPAARRRLSLRGRGLFSLRGLRAHQRSHSSGGSTSPGCTHH
    DSMDPSDEEGRGGAGGGGAGSEHSETLSSLSLTSLFCPPPPPPAPGLTPA
    RKFSSTSSLAAPGRPHAAALAHGLARSPSWAADRSKDPPGRAPLPMGLGP
    LAPPPQPLPGELEPGDAASKRKR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CACNA1I
  • Full Name
  • Calcium voltage-gated channel subunit alpha1 I
  • Introduction
  • This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants.
  • Alternative Names
  • Cav3.3; ca(v)3.3; voltage-dependent T-type calcium channel subunit alpha-1I; calcium channel, voltage-dependent, T type, alpha 1I subunit; calcium channel, voltage-dependent, alpha 1I subunit; voltage-gated calcium channel subunit alpha Cav3.3; CACNA1I; Calcium voltage-gated channel subunit alpha1 I

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