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Magic™ Membrane Protein Human CACNA2D4 (Calcium voltage-gated channel auxiliary subunit alpha2delta 4) Full Length (CAT#: MPC0433K) Made to Order

This product is a 127.9 kDa Human CACNA2D4 membrane protein expressed in HEK293. The protein is for research use only and is not approved for use in humans or in clinical diagnosis.

Product Specifications

  • Host Species
  • Human
  • Target Protein
  • CACNA2D4
  • Protein Length
  • Full length
  • Protein Class
  • Transporter; Ion channel
  • Molecular Weight
  • 127.9 kDa
  • TMD
  • 1
  • Sequence
  • MVCGCSALLPLPNPRPTMPATPNFLANPSSSSRWIPLQPMPVAWAFVQKT
    SALLWLLLLGTSLSPAWGQAKIPLETVKLWADTFGGDLYNTVTKYSGSLL
    LQKKYKDVESSLKIEEVDGLELVRKFSEDMENMLRRKVEAVQNLVEAAEE
    ADLNHEFNESLVFDYYNSVLINERDEKGNFVELGAEFLLESNAHFSNLPV
    NTSISSVQLPTNVYNKDPDILNGVYMSEALNAVFVENFQRDPTLTWQYFG
    SATGFFRIYPGIKWTPDENGVITFDCRNRGWYIQAATSPKDIVILVDVSG
    SMKGLRMTIAKHTITTILDTLGENDFINIIAYNDYVHYIEPCFKGILVQA
    DRDNREHFKLLVEELMVKGVGVVDQALREAFQILKQFQEAKQGSLCNQAI
    MLISDGAVEDYEPVFEKYNWPDCKVRVFTYLIGREVSFADRMKWIACNNK
    GYYTQISTLADTQENVMEYLHVLSRPMVINHDHDIIWTEAYMDSKLLSSQ
    AQSLTLLTTVAMPVFSKKNETRSHGILLGVVGSDVALRELMKLAPRYKLG
    VHGYAFLNTNNGYILSHPDLRPLYREGKKLKPKPNYNSVDLSEVEWEDQA
    ESLRTAMINRETGTLSMDVKVPMDKGKRVLFLTNDYFFTDISDTPFSLGV
    VLSRGHGEYILLGNTSVEEGLHDLLHPDLALAGDWIYCITDIDPDHRKLS
    QLEAMIRFLTRKDPDLECDEELVREVLFDAVVTAPMEAYWTALALNMSEE
    SEHVVDMAFLGTRAGLLRSSLFVGSEKVSDRKFLTPEDEASVFTLDRFPL
    WYRQASEHPAGSFVFNLRWAEGPESAGEPMVVTASTAVAVTVDKRTAIAA
    AAGVQMKLEFLQRKFWAATRQCSTVDGPCTQSCEDSDLDCFVIDNNGFIL
    ISKRSRETGRFLGEVDGAVLTQLLSMGVFSQVTMYDYQAMCKPSSHHHSA
    AQPLVSPISAFLTATRWLLQELVLFLLEWSVWGSWYDRGAEAKSVFHHSH
    KHKKQDPLQPCDTEYPVFVYQPAIREANGIVECGPCQKVFVVQQIPNSNL
    LLLVTDPTCDCSIFPPVLQEATEVKYNASVKCDRMRSQKLRRRPDSCHAF
    HPEENAQDCGGASDTSASPPLLLLPVCAWGLLPQLLR

Product Description

  • Expression Systems
  • HEK293
  • Tag
  • Flag-StrepII or based on specific requirements
  • Protein Format
  • Detergent or based on specific requirements

Target

  • Target Protein
  • CACNA2D4
  • Full Name
  • Calcium voltage-gated channel auxiliary subunit alpha2delta 4
  • Introduction
  • This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
  • Alternative Names
  • RCD4; voltage-dependent calcium channel subunit alpha-2/delta-4; calcium channel, voltage-dependent, alpha 2/delta subunit 4; voltage-gated calcium channel alpha(2)delta-4 subunit; voltage-gated calcium channel subunit alpha-2/delta-4; CACNA2D4; Calcium voltage-gated channel auxiliary subunit alpha2delta 4

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